Search results for "Topical therapy"

showing 2 items of 2 documents

An evaluation of the efficacy of a topical gel with Triester Glycerol Oxide (TGO) in the treatment of minor recurrent aphthous stomatitis in a Turkis…

2017

Background Triester glycerol oxide gel (Protefix® Queisser Pharma, Germany) is a new topical agent that has the property of adherence to the oral mucosa by forming a lipid film which protects against mechanical trauma and may help to reduce oral tissue moisture loss and inflammation. The aim of this clinical trial was to determine the efficacy of a topical TGO gel and to also compare it with triamcinolone acetonide pomade in the treatment of minor recurrent aphthous stomatitis. Material and Methods This study was a randomized, double-blind, placebo-controlled clinical trial and 180 patients with the complaint of minor aphthous ulcers were enrolled in this study. The sociodemographic data an…

MaleTriamcinolone acetonideTurkeyAdministration TopicalTABLETStriamcinolone acetonideminor recurrent aphthous stomatitisDISEASEOintmentsULCERATION0302 clinical medicineRecurrenceOral mucosaYoung adultMiddle Aged:CIENCIAS MÉDICAS [UNESCO]030205 complementary & alternative medicineTreatment Outcomemedicine.anatomical_structureULCERSCohortUNESCO::CIENCIAS MÉDICASTopical therapyFemaleStomatitis Aphthousmedicine.drugAdultmedicine.medical_specialtyAdolescentRecurrent aphthous stomatitisPlaceboDouble blindYoung Adult03 medical and health sciencesDouble-Blind MethodInternal medicinemedicinetriester glycerol oxideMANAGEMENTHumansGlucocorticoidsGeneral DentistryAgedOral Medicine and Pathologybusiness.industryResearch030206 dentistrySurgeryClinical trialOtorhinolaryngologySurgeryLASERbusinessGelsPASTE
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Topical therapies for oral lichen planus management and their efficacy: a narrative review.

2012

Oral Lichen Planus (OLP) is a chronic inflammatory condition implicating T cell-mediated cytotoxicity, and involving oral mucosal surfaces. Several therapeutic regimens have been evaluated to treat OLP and pain related, but often without high level of evidence. Topical formulations are the favourite for the majority of cases; bioadhesive formulations have been considered very useful and practical for local drug delivery in oral mucosa, due to the increased residence time on the oral mucosa of the dosage forms and better therapeutic efficacy. In this narrative review, authors try to illustrate the current topical managements for OLP from the accessible literature on this topic. Steroids are …

medicine.medical_specialtyOral Lichen Planus topical therapy corticosteroids aloe vera retinoids hyaluronic acid phototherapy laser therapy.Time FactorsBasiliximabHyaluronic acidAdministration TopicalEfalizumabPimecrolimusRetinoidsDrug Delivery Systemsstomatognathic systemSettore MED/28 - Malattie OdontostomatologicheDrug DiscoveryOral and maxillofacial pathologymedicineCorticosteroidsHumansAloe vera; Corticosteroids; Hyaluronic acid; Laser therapy; Oral lichen planus; Phototherapy; Retinoids; Topical therapy; Drug Discovery3003 Pharmaceutical Science; PharmacologyPharmacologybusiness.industryDrug Discovery3003 Pharmaceutical ScienceMouth MucosaPhototherapymedicine.diseaseDermatologyAloe veraAlefaceptTacrolimusInfliximabstomatognathic diseasesPhotopheresisOral lichen planusQuality of LifeTopical therapyOral lichen planusLaser Therapybusinessmedicine.drugLichen Planus Oral
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